METHYL N-(TERT-BUTOXYCARBONYL)-(2S, 4R)-4-FLUOROPROLINATE - Names and Identifiers
Name | N-Boc-trans-4-fluoro-L-proline methyl ester
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Synonyms | BOC-TRANS-4-FLUORO-L-PROLINE METHYL ESTER (4R)-1-BOC-4-FLUORO-L-PROLINE METHYL ESTER N-Boc-trans-4-fluoro-L-proline methyl ester N-T-BOC-TRANS-4-FLUORO-L-PROLINE METHYL ESTER (2S,4R)-N-Boc-trans-4-fluoro-L-proline methyl ester METHYL N-(TERT-BUTOXYCARBONYL)-(2S, 4R)-4-FLUOROPROLINATE 1-tert-Butyl 2-methyl (2S,4R)-4-fluoropyrrolidine-1,2-dicarboxylate 1-tert-Butyl 2-methyl (2S,4R)-4-fluoro-1,2-pyrrolidinedicarboxylate (2S,4R)-4-fluoropyrrolidine-1,2-dicarboxylic acid O1-tert-butyl ester O2-methyl ester 1,2-pyrrolidinedicarboxylic acid, 4-fluoro-, 1-(1,1-dimethylethyl) 2-methyl ester, (2S,4R)-
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CAS | 203866-18-6
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InChI | InChI=1/C11H18FNO4/c1-11(2,3)17-10(15)13-6-7(12)5-8(13)9(14)16-4/h7-8H,5-6H2,1-4H3/t7-,8+/m1/s1 |
METHYL N-(TERT-BUTOXYCARBONYL)-(2S, 4R)-4-FLUOROPROLINATE - Physico-chemical Properties
Molecular Formula | C11H18FNO4
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Molar Mass | 247.26 |
Density | 1.16 |
Melting Point | 34-39 °C |
Boling Point | 296.5°C at 760 mmHg |
Flash Point | 110°C |
Water Solubility | Insoluble in water. |
Vapor Presure | 0.00143mmHg at 25°C |
Storage Condition | 2-8°C |
Refractive Index | 1.465 |
METHYL N-(TERT-BUTOXYCARBONYL)-(2S, 4R)-4-FLUOROPROLINATE - Risk and Safety
METHYL N-(TERT-BUTOXYCARBONYL)-(2S, 4R)-4-FLUOROPROLINATE - Introduction
N-Boc-trans-4-fluoro-L-proline methyl ester is an organic compound whose chemical structural formula is N-Boc-trans-4-fluoro-l-prolin-och3.
N-Boc-trans-4-fluoro-L-proline methyl ester is a solid compound, usually colorless or slightly yellow crystal. It has good solubility and is soluble in some organic solvents, such as methanol and dimethylthionamide.
N-Boc-trans-4-fluoro-L-proline methyl ester has important applications in organic synthesis. It can be used as an intermediate in drug synthesis for the synthesis of physiologically active compounds. It has also been used to synthesize new drugs with antiviral and antitumor activity.
The preparation method of N-Boc-trans-4-fluoro-L-proline methyl ester is usually realized by reacting the existing trans-4-fluoro-L-proline with methanol and adding N-Boc protecting groups.
When using N-Boc-trans-4-fluoro-L-proline methyl ester in the laboratory, you need to pay attention to its safety. It is irritating and direct contact with skin and eyes should be avoided. Appropriate personal protective equipment, such as lab gloves and goggles, should be worn during operation. In addition, it should be operated in a well-ventilated place to avoid inhalation of vapors. Store it in a dry, cool place, away from fire and oxidizing agents.
In General, N-Boc-trans-4-fluoro-L-proline methyl ester is an organic compound with important application value, it is necessary to pay attention to safe operation when using it.
Last Update:2024-04-09 20:52:54